It's on sale now, priced from £63,790 for the saloon. This is an increase of over £15,000 over the E43 that comes largely thanks to the new car's more complex powertrain. The new E53 estate makes the same jump to start at £65,790.
The coupé splits the difference at £64,790, while the cabriolet is the most expensive at £69,285. The 53-badged models are the punchiest and most expensive to be offered on the two-door E-Class variants, as Mercedes does not offer the full-fat AMG 63 variant beyond the saloon and estate.
In addition to the newly announced prices, Mercedes has also replaced the E350d with a new E400d 4Matic, which starts at £52,685 in saloon form. The estate carries a £2000 premium over this. The E400d uses a new 3.0-litre diesel straight six, producing 335bhp - up from the E350d's 258bhp - and 516lb ft of torque to the 350d's 457. 48.7mpg and 154g/km CO2 are claimed, as is a 4.9sec dash to 62mph.