Manor will not race in the 2017 Formula 1 season because no buyer has been found to save the team.
Manor's parent company, Just Racing Services, was placed into administration by FRP Advisory on 6 January and 20 January was initally set as the deadline for finding a buyer. It ceased trading on Friday, according to reports by the BBC.
Staff at the team's factory in Banbury, Oxfordshire will be made redundant after salaries for January have been paid.
Numerous parties were rumoured to be interested, including Indonesian businessman Ricardo Galael, Bernie Ecclestone business partner Tavo Hellmund, a consortium of Asian buyers and ex-McLaren chairman Ron Dennis.
There had been hope for the team after the FIA gave it permission to start the upcoming season with its 2016 car modified to meet the new regulations, although a 2017 car had been designed.
The team's fate was sealed at the penultimate grand prix of the 2016 season when the Sauber team scored two points, which relegated Manor to 11th in the constructors' championship and effectively lost them £30 million in prize money that was vital for the team's survival.