Underpinning the pick-up is an all-new, high-strength steel frame, on which sits an aluminium-alloy body. The use of alloys helps cut weight by 318kg, compared to the current model, improving performance and economy.
Four engines will be offered in the latest F150 line-up. A new 2.7-litre turbocharged 'EcoBoost' petrol joins the existing 3.5-litre EcoBoost; Ford will also offer a naturally aspirated 3.5-litre V6 and a naturally aspirated 5.0-litre V8.
EcoBoost versions of the F150 benefit further from the addition of 'Active Grille Shutters', which work to boost efficiency by closing at speed to reduce drag. All feature electronic power-assisted steering, which further helps to cut fuel consumption.
A six-speed automatic gearbox is standard on all models; power is sent to the rear wheels, or to all four on higher-specification models.
The F150 is one of Ford's most popular pick-ups, with it achieving the heady status of being America's best-selling pick-up for 37 consecutive years. It's not just popular with those seeking a practical work vehicle either; in fact the F150 was America's best-selling car overall for some 32 years too.
Ford says that the new 2015 F150 has undergone a series of gruelling trials and torture tests in order to ensure its durability and continued success. Test mules are claimed to have covered some 10 million miles, undergoing trials, and even participated - in disguised form - in the Baja 1000 rally.
"More than ever before, customers want a truck that is a dependable partner, mobile office and a go-anywhere workshop," said Raj Nair, Ford group vice president, Global Product Development.
"To meet the needs of our truck customers, we created smart new features and a whole new approach to using advanced materials and engines to improve capability and efficiency."
New technology includes a 360-degree camera view, an 8-inch LCD display for the infotainment system, integrated loading ramps for the pick-up bed, LED headlights, side-view mirror spotlights and 400-watt power outlets inside the cab.
Careful thought has also been put into improving the ease of use of the new F150. For example, the cargo box benefits from integrated LED lighting, making it easier and quicker to find what you're looking for.
Interior upgrades are extensive, with a focus on comfort and practicality. Ford says that the cabin now offers more legroom for rear occupants, while the vehicle's controls are optimised for use by those wearing heavy gloves, and numerous storage points are on offer - including laptop stowage in the centre console.
Ford has also worked to make the F150 safer, by adding options including adaptive cruise control, blind spot warning and lane-keeping assist.
Myriad trim levels and body styles will be offered, alongside an 'FX4' off-road package that adds an electronic locking rear differential, skid plates and upgraded shock absorbers.
"The F150 is well-known for being Built Ford Tough. Now, it is both tough and smart," said Mark Fields, Ford Motor Company chief operating officer.